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The development and marketing of antibiotics


Keywords: antibiotics, penicillin, cephalosporins, R & D, marketing, forecasting, competitive Abstract: recent years, the world's antibiotic market, average annual growth rate of 8% about the global antibiotics market share of approximately 250 to 260 billion U.S. dollars, major pharmaceutical companies have invested heavily in the development of antibiotics, new antibiotics continue to appear. In the Chinese pharmaceutical market, anti-infective drugs for many years has ranked first in sales, with annual sales of more than 200 billion yuan, accounting for 30% of drug sales, the National 6700 National Drug manufacturing enterprises, more than 1,000 Home production of various kinds of antibiotics, the products very competitive. [Abstract]: In recent years, the average annual growth of the antibiotic market of the world is about 8%, the market share of the global antibiotic is about 25060 hundred million dollars, every large pharmacy enterprise invest the research and development that a huge sum of money carried on the antibiotic medicine one after another, make the antibiotic new product appear constantly. In the medical market of China, have resisted and infected medicines and already occupied the primary importance of the sales amount for years, annual sales amount for 20 billion more than, account for national medicines 30% of sales amount, the whole country 6700 country among the manufacturing enterprise medicines, more than 1000 produce all kinds of antibiotic, the products are unusually fierce in competition. [Key words]: The antibiotic, penicillin, hair spore have plain fungus, researches and develops, the market, predicts, competition microbial metabolism of antibiotics is products by fungi, bacteria or other biological reproductive process in a class generated by killing or inhibiting microbial growth substances, synthetic methods can also be manufactured in very small doses can inhibit or kill pathogenic microorganisms . Penicillin used clinically since 1940, has reached thousands of types of antibiotics, is also commonly used in clinical hundreds of species, mainly from the microbial culture broth or synthetic, semi-synthetic method of manufacture, the following several categories: (a) β-lactam (b) aminoglycoside (c) tetracycline (d) chloramphenicol class (e) Large macrolides (VI) on the G + bacteria to other antibiotics (g) acting on G bacteria to other antibiotics (h) anti-fungal antibiotic (ix) anti-tumor antibiotics <BR Pharmaceutical industry, chemical raw materials in 2004 a significant decline in overall profit. The first 10 months, chemical raw materials sales revenue of 57.627 billion yuan, an increase of 16.62%, but a drop in profits, down 14.16%. Pharmaceutical industrial output value increased 25.54% or so, about 511.311 billion yuan; chemical sales increased 16.54% or so, about 174.816 billion yuan. Combination of all favorable and unfavorable factors, we expect fourth quarter 2004 and first quarter of 2005 will be the best period of development of the pharmaceutical industry. Chemical and pharmaceutical companies should seize this good opportunity to promote the rapid development of the industry. China's pharmaceutical enterprises exist many small, rigid management, low efficiency, high cost, poor efficiency, order and chaos, and other major issues, the implementation of other provisions as the WTO, foreign pharmaceutical companies increased domestic competition, China's chemical system How drug companies face bigger and stronger, develop their own unique competitive advantage realistic choice. Anti-infective drugs sales of anti-infective drugs account for 15% of the world about drug sales, ranking No. 2. According to the survey data show that worldwide anti-infective market is roughly the proportion: 31% Americas, Asia 31%, 27% in Europe, Africa and Oceania accounted for about 11%. The face of evolving drug trends and the increasingly fierce market competition, all competing countries in the world pharmaceutical development and introduction of new products, with greater advantages for occupying the market, but also active in pharmaceutical market research in order to obtain research and development the best results.

sales from the U.S. anti-infective situation, cephalosporins champion, 45%; followed by penicillin and 15%; third quinolones accounted for 12%; Tai Wan lactone as the fourth, 6%; tetracycline class for the fifth, accounting for 5%; other category accounted for 17%. It is worth mentioning that in recent years, sales of quinolones and macrolides showed a rising trend, according to analysis and accelerated new drug development, new products onto the market related. Tetracycline is gradually shrinking sales, the main varieties of the old medicines, and a larger proportion of toxic side effects, impact on market sales. Recent years, fierce competition in the international market of antibiotics, new varieties continue to market, shorter product life cycles. Relevant authority that the antibiotic from the current development trend, although the advance and retreat the world market of antibiotics, but the overall trend is slowing. Present, the global antibiotics market, the limited room for growth, coupled with new products market, the market increasingly competitive. Gradual improvement in the national environmental sanitation conditions, but also with the pathogen under control, so that the gradual reduction of the use of antibiotics, on the other hand, humans after long-term use of antibiotics, also recognizes the serious consequences of overuse of antibiotics, it is more on the use of antibiotics become more cautious. Penicillin trends discussed China Association of Pharmaceutical Commerce believes that the current pharmaceutical market in China has the following basic features. First, the needs of society steady growth rate slowed. Natural increase of population, aging population, rural-urban migration, increased investment in health is a factor of four irreversible steady growth in the domestic pharmaceutical market, the basic conditions. 1998 births nationwide in 1991 people, the elderly population over 65 years to reach 8375 million, which is based on the pharmaceutical market and increased vitality. However, due to lower income growth and lower than the rate of national economic development, urban and rural areas there are a lot of surplus labor. In particular, health care, education, housing and other personal items to pay increase, so that residents tend to decrease current consumption, consumer behavior is more cautious, so that the whole society consumer demand slowdown in growth, also showed an increase of pharmaceutical consumption demand slowing trend. The second is the pharmaceutical retail market continues to flourish. Third untapped rural market. Especially the central development of the western development strategy, the western people's health care level will be further raised, the majority of the pharmaceutical market will be further active again. Fourth, the development of the pharmaceutical market imbalance, regional disparities continue to widen. Fifth, the structure of drug sales showed sales of imported drugs down, joint drug steady growth trend of increasing domestic drug increases. Meanwhile, China Association of Pharmaceutical Commerce survey showed that consumption of drugs during the first half of 1998 constitutes a ratio of supply: drugs accounted for 57.22% of domestic joint ventures accounted for 29.33% drug, drug imports accounted for 13.45%. From drug categories, anti-infective antibiotics accounted for 35.78%, ranking first. In the anti-infective drugs in the penicillin class occupy the first place, accounting for 42.38%. Specific varieties from the point of view, sales of drugs top ten were: penicillin needle, Domperidone tablets, cefazolin needle, Contac capsules, cefuroxime sodium needle, Fenbid capsules, human serum albumin-pin , gliclazide tablets, fat emulsion, amoxicillin. Penicillin re-sort the needle jumped first. According to the above situation, and penicillin industrial and domestic clinical use, we believe that: 1. The domestic pharmaceutical market could turn introduction of new medical insurance system, foreign investment, private enterprises and individual employees will be covered by medical Insurance category; National Essential Drug List of the basic Medicare drug will make that effective, reliable, inexpensive drugs account for a large market share; pharmaceutical sub-industry, medical institutions and pharmaceutical marketing is cut off economic ties between the unified prices, healthy competition, so that drugs will have a greater development of retail space; the product as the leading pharmaceutical companies, large companies, combined with the reorganization of large groups, to enable enterprises to increase the organizational restructuring, strengthening market competitiveness; countries Economic and Trade Commission on the strict control of imports and strictly control the newly established pharmaceutical companies, on the low level of excess production capacity resolutely tight compression strategy to stop the repeat and build a system to regularly publish long-term products will gradually achieve economic medicine aggregate demand and aggregate supply the basic balance, medicine blind competition in commodity markets will be effectively curbed, and the pharmaceutical market circulation order sight better. In 1999, for example, the normal demand for the country penicillin needles 60 to 65 million, which is produced in the first quarter to 1.8 billion (normal is 1.6 billion), more than 12% of social demand. Thus, under the pressure in the market, the price of penicillin needle down again in the second quarter,[link widoczny dla zalogowanych], 20% cut. Production until the fourth quarter before transferring to level control in 6.2 billion year, compared to 1998 decreased by 5% by adjusting supply and demand, prices have stabilized. Currently, 80 million units of sodium penicillin prices basically stable at 0.31 to 0.40 yuan.

2. penicillin antibiotics have good